GENERAL CATALOGUE
INCB16562
HY-111077 · 50 mg
MedChemExpress · Cat: HY-111077
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medchemexpress.com/incb16562.html
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Catalog No: HY-111077
CAS No: 933768-63-9
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
INCB16562 is an orally active and selective inhibitor against JAK1/2 markedly selective over JAK3. INCB16562 potently inhibits interleukin-6 IL-6 -induced phosphorylation of STAT3. Additionally, INCB16562 inhibits the proliferation and survival of myeloma cells dependent on IL-6 for growth, as well as the IL-6AAasAasAainduced growth of primary bone marrow-derived plasma cells. INCB16562 antagonizes the growth of myeloma xenografts in mice with antitumor activity. INCB16562 is promising for research of multiple myeloma.
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