GENERAL CATALOGUE
Indibulin
HY-13649 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13649
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Catalog No: HY-13649
CAS No: 204205-90-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Indibulin ZIO 301 , an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.
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