Influenza A virus-IN-14

Description

Influenza A virus-IN-14 Compound 37 is an inhibitor for influenza virus type A IAV , which inhibits H1N1 with an EC50 of 23 nM. Influenza A virus-IN-14 exhibits low cytotoxicity with CC50 of more than 100 ?M. Influenza A virus-IN-14 inhibits cytopathic effect and improves the survival rates of cell Calu3. Influenza A virus-IN-14 exhibits synergistic activity with the neuraminidase inhibitor Oseltamivir HY-13317 . Influenza A virus-IN-14 exhibits poor pharmacokinetic properties in CD-1 mouse.