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Ingenol 3,20-dibenzoate
GENERAL CATALOGUE

Ingenol 3,20-dibenzoate

HY-137295 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-137295

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Catalog No: HY-137295
CAS No: 59086-90-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Ingenol 3,20-dibenzoate is a potent protein kinase C PKC isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-? production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells.

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