GENERAL CATALOGUE
Inobrodib
HY-111784 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-111784
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medchemexpress.com/CCS-1477.html
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Catalog No: HY-111784
CAS No: 2222941-37-7
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Inobrodib CCS1477 is an orally active, potent, and selective inhibitor of the p300/CBP bromodomain. Inobrodib binds to p300 and CBP with Kd values of 1.3 and 1.7 nM, respectively, and with 170/130-fold selectivity compared with BRD4 with a Kd of 222 nM. CCS1477 inhibits cell proliferation in prostate cancer cell lines and decreases androgen receptor AR - and C-MYC-regulated gene expression.
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