GENERAL CATALOGUE
Inosine-5'-diphosphate
HY-149101 · 25 mg
MedChemExpress · Cat: HY-149101
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medchemexpress.com/riboxin.htmlCatalog No: HY-149101
CAS No: 86-04-4
Category: Metabolic Enzyme Protease
Pack Size: 25 mg
Brand: MedChemExpress
Description
Inosine-5-diphosphate IDP is a decoy substrate of NM23-H2. Inosine-5-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 KD: 5.0 ?M . Inosine-5-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of ?-irradiation. Inosine-5-diphosphate can be used for cancers like Burkitts lymphoma and cardiovascular diseases research.
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