BioMall
Brand Store/MedChemExpress/Ipatasertib tosylate
Ipatasertib tosylate
GENERAL CATALOGUE

Ipatasertib tosylate

HY-15186C · 50 mg

MedChemExpress · Cat: HY-15186C

Reach 3+ verified distributors

Catalog No: HY-15186C
CAS No: 1491138-24-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Ipatasertib GDC-0068 tosylate is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib tosylate synchronously activates FoxO3a and NF-?B through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib tosylate also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models.

More from MedChemExpress

2-Bromohexadecanoic acid
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HDAC-IN-84
HY-170379
Apoptosis