GENERAL CATALOGUE
IRAK4-IN-21
HY-151363 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-151363
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medchemexpress.com/irak4-in-21.htmlCatalog No: HY-151363
CAS No: 2170694-04-7
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
IRAK4-IN-21 compound 17 is an orally active, potent and selective IRAK4 inhibitor with IC50 values of 5 and 56 nM for IRAK4 and TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production IC50=0.17 ?M and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis.