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Irdabisant
GENERAL CATALOGUE

Irdabisant

HY-109968 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-109968

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Manufacturer product page

medchemexpress.com/irdabisant.html
Catalog No: HY-109968
CAS No: 1005402-19-6
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Irdabisant CEP-26401 is a selective, orally active and blood-brain barrier BBB penetrant histamine H3 receptor H3R inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC50 of 13.8 ?M. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment.

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