GENERAL CATALOGUE
IRE1? kinase-IN-2
HY-18509 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-18509
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medchemexpress.com/ire1%CE%B1-kinase-in-2.htmlCatalog No: HY-18509
CAS No: 1414938-21-8
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
IRE1? kinase-IN-2 is a potent IRE1? kinase inhibitor, with an EC50 of 0.82 ?M. IRE1? kinase-IN-2 inhibits IRE1? kinase autophosphorylation IC50=3.12 ?M . IRE1? kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.