

HY-171007 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-171007
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medchemexpress.com/irf1-in-2.htmlDescription
IRF1-IN-2 Compound I-19 is an IRF1 inhibitor. IRF1-IN-2 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-2 inhibits cell death signaling pathway i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1; inhibits the Pho of TKB1, upregulates GPX4 and downregulates FACL4 . IRF1-IN-2 has a protective effect on ionizing radiation-induced inflammatory skin injury.







