GENERAL CATALOGUE
Iruplinalkib
HY-145574 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-145574
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medchemexpress.com/iruplinalkib.html
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Catalog No: HY-145574
CAS No: 1854943-32-0
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Iruplinalkib WX-0593 is an orally active and selective ALK/ROS1 inhibitor. Iruplinalkib can effectively inhibit tyrosine autophosphorylation of ALK and mutant ALK, EGFR, with the IC50 between 5.38 and 16.74 nM. Iruplinalkib is also a suppressive agent of the transporter MATE1, MATE2K, P-gp and BCRP. Iruplinalkib can be used in the study of non-small cell lung cancer.
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