GENERAL CATALOGUE
Isatuximab
HY-P9976 · 1 mg
MedChemExpress · Cat: HY-P9976
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medchemexpress.com/isatuximab.html
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Catalog No: HY-P9976
CAS No: 1461640-62-9
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38, a protein highly expressed on hematological malignant cells, including those in multiple myeloma MM . Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions.
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