GENERAL CATALOGUE
Isoniazid
CS-O-10901 ·
Clearsynth · Cat: CS-O-10901
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Catalog No: CS-O-10901
CAS No: 54-85-3
Category: Isoniazid
Brand: Clearsynth
Description
Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic Nacetyltransferase NAT and cytochrome P450 2E1 CYP2E1 to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial tuberculostatic .
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