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ITF5924
GENERAL CATALOGUE

ITF5924

HY-161306 · 50 mg

MedChemExpress · Cat: HY-161306

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medchemexpress.com/itf5924.html
Catalog No: HY-161306
CAS No: 2760854-72-4
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

ITF5924 compound 1 is a potent and highly selective HDAC6 inhibitor with an IC50 of 7.7 nM. ITF5924 shows greater than 104-fold selectivity for HDAC6 over all other HDAC subtypes. ITF5924 containing a difluoromethyl-1,3,4-oxadiazole DFMO moiety is slow-binding substrate analog of HDAC6 that undergo an enzyme-catalyzed ring opening reaction, forming a tight and long-lived enzyme-inhibitor complex.

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