

HY-161306 · 50 mg
MedChemExpress · Cat: HY-161306
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Manufacturer product page
medchemexpress.com/itf5924.html
Description
ITF5924 compound 1 is a potent and highly selective HDAC6 inhibitor with an IC50 of 7.7 nM. ITF5924 shows greater than 104-fold selectivity for HDAC6 over all other HDAC subtypes. ITF5924 containing a difluoromethyl-1,3,4-oxadiazole DFMO moiety is slow-binding substrate analog of HDAC6 that undergo an enzyme-catalyzed ring opening reaction, forming a tight and long-lived enzyme-inhibitor complex.





