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ITK Stable Ba/F3 Cell Line
GENERAL CATALOGUE

ITK Stable Ba/F3 Cell Line

T3148 · 1 x 106 cells / 1.0 mL

abm good · Cat: T3148

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Catalog No: T3148
Category: Cellular Materials
Pack Size: 1 x 106 cells / 1.0 mL
Brand: abm good

Description

Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The ITK Stable Ba/F3 Cell Line expresses activated human ITK tyrosine kinase that is linked to a GFP reporter GFP-ETV6-ITK in MSCV-puro . Even though this cell line expresses activated tyrosine, it is non-transforming, meaning that the cells still require IL-3 to grow.

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