

HY-17514S1 · 1 mg
MedChemExpress · Cat: HY-17514S1
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medchemexpress.com/itraconazole-d3.html
Description
Itraconazole-d3 R51211-d3 is the deuterium labeled Itraconazole HY-17514 . Itraconazole R51211 is a triazole antifungal agent and a potent and orally active Hedgehog Hh signaling pathway antagonist with an IC50 of 800 nM. Itraconazole potently inhibits lanosterol 14?-demethylase cytochrome P450 enzyme , thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein OSBP inhibitor.







