

HY-17514 · 100 mg
MedChemExpress · Cat: HY-17514
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Manufacturer product page
medchemexpress.com/Itraconazole.html
Description
Itraconazole R51211 is a triazole antifungal agent and a potent and orally active Hedgehog Hh signaling pathway antagonist with an IC50 of 800 nM. Itraconazole potently inhibits lanosterol 14?-demethylase cytochrome P450 enzyme , thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein OSBP inhibitor.







