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Ivaltinostat formic
GENERAL CATALOGUE

Ivaltinostat formic

HY-16138A · 1 mg

MedChemExpress · Cat: HY-16138A

₹390 – ₹600 approx.This price excludes freight and taxes. Please RFQ to get the final price.

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Catalog No: HY-16138A
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

Ivaltinostat CG-200745 formic is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat formic inhibits deacetylation of histone H3 and tubulin. Ivaltinostat formic induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 Waf1/Cip1 proteins. Ivaltinostat formic enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine HY-16138 and 5-Fluorouracil 5-FU; HY-90006 . Ivaltinostat formic induces apoptosis and has anti-tumour effects.

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