GENERAL CATALOGUE
Ivarmacitinib
HY-112724 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-112724
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Manufacturer product page
medchemexpress.com/ivarmacitinib.htmlCatalog No: HY-112724
CAS No: 1445987-21-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ivarmacitinib SHR0302 is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects.
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