GENERAL CATALOGUE
Ivarmacitinib sulfate
HY-112724A · 50 mg
MedChemExpress · Cat: HY-112724A
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medchemexpress.com/ivarmacitinib-sulfate.html
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Catalog No: HY-112724A
CAS No: 1639419-51-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Ivarmacitinib SHR0302 sulfate is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects.
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