

HY-P99675 · 1 mg
MedChemExpress · Cat: HY-P99675
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medchemexpress.com/ivonescimab.htmlDescription
Ivonescimab AK112 is a PD-1/VEGF bispecific antibody. Ivonescimab competitively inhibiting PD-1/PD-L1 interaction, reversing the immunosuppression mediated by it, and blocks the binding of VEGF-A to VEGFR2, inhibiting tumour angiogenesis in the tumour microenvironment. Ivonescimab also has significantly anticancer activity against EGFR-mutated locally advanced or metastatic non-squamous non-small cell lung cancer NSCL .