GENERAL CATALOGUE
IWP-2
HY-13912 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-13912
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Catalog No: HY-13912
CAS No: 686770-61-6
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine Porcn and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1? inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1?.
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