GENERAL CATALOGUE
J-113863
HY-103360 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103360
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medchemexpress.com/j-113863.htmlCatalog No: HY-103360
CAS No: 353791-85-2
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
J-113863 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8?nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 IC50 of 0.58 nM , but a weak antagonist of the mouse CCR3 IC50 of 460 nM . J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-? receptors. Anti-inflammatory effect.
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