GENERAL CATALOGUE
J22352
HY-126147 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-126147
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/j22352.html
Sponsored
Catalog No: HY-126147
CAS No: 2252395-44-9
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
J22352 is a PROTAC proteolysis-targeting chimeras -like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM. J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor immune response in glioblastoma cancers, and leading to the restoration of host antitumor activity by reducing the immunosuppressive activity of PD-L1.