GENERAL CATALOGUE
JAB-2485
HY-157396 · 1 mg
MedChemExpress · Cat: HY-157396
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Manufacturer product page
medchemexpress.com/jab-2485.htmlCatalog No: HY-157396
CAS No: 2899209-55-1
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
JAB-2485 is an orally active and selective Aurora kinase A AURKA inhibitor with an IC50 value of 0.327 nM. JAB-2485 exhibits inhibitory activity against various tumor cell lines such as neuroblastoma, triple-negative breast cancer, small cell lung cancer, and epithelial ovarian cancer. JAB-2485 can induce cell cycle arrest and apoptosis in tumor cells. JAB-2485 has antitumor activity.
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