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JAK/HDAC-IN-4
GENERAL CATALOGUE

JAK/HDAC-IN-4

HY-169290 · 50 mg

MedChemExpress · Cat: HY-169290

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medchemexpress.com/jak-hdac-in-4.html
Catalog No: HY-169290
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

JAK/HDAC-IN-4 compound 11 i is a JAK/HDAC inhibitor with the IC50 values of 0.49 nM and 12 nM for JAK2 and HDAC6, respectively. JAK/HDAC-IN-4 inhibits the cell proliferation and the production of nitric oxide. JAK/HDAC-IN-4 ameliorates psoriasis-like skin lesions in an Imiquimod HY-B0180 -induced murine model with low toxicity.

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