

HY-16641 · 50 mg
MedChemExpress · Cat: HY-16641
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medchemexpress.com/jak1-in-17.htmlDescription
JAK1-IN-17 Compound 31 is a highly selective inhibitor of JAK1 with a Ki of 1.9 nM. JAK1-IN-17 exhibits a low whole blood shift, which allows maintaining good whole blood potency. JAK1-IN-17 is also a nitrile-containing analogue with consistent, yet weak reversible inhibition of CYP3A4 using a midazolam probe IC50 = 7.9 ?M . JAK1-IN-17 can be studied in cancer research.

