BioMall
Brand Store/MedChemExpress/JAK1/TYK2-IN-3
JAK1/TYK2-IN-3
GENERAL CATALOGUE

JAK1/TYK2-IN-3

HY-143885 · 50 mg

MedChemExpress · Cat: HY-143885

Reach 3+ verified distributors

Catalog No: HY-143885
CAS No: 2734918-37-5
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

JAK1/TYK2-IN-3 is a potent, selective and orally active dual TYK2/JAK1 inhibitor with IC50 values of 6 and 37 nM, respectively. JAK1/TYK2-IN-3 also shows selectively relative to JAK2 IC50=140 nM and JAK3 IC50=362 nM . JAK1/TYK2-IN-3 shows anti-inflammatory effect by regulating the expression of related TYK2/JAK1-regulated genes, as well as the formation of Th1, Th2, and Th17 cells.

More from MedChemExpress

hsa-miR-4268 antagomir
hsa-miR-4268 antagomir
HY-RI00947A
Epigenetics
hsa-miR-4731-5p antagomir
hsa-miR-4731-5p antagomir
HY-RI01332A
Epigenetics
FRMD3 Human Pre-designed siRNA Set A
FRMD3 Human Pre-designed siRNA Set A
HY-RS05100
Epigenetics
MAPK12 Human Pre-designed siRNA Set A
MAPK12 Human Pre-designed siRNA Set A
HY-RS08101
Epigenetics
NEURL1 Human Pre-designed siRNA Set A
NEURL1 Human Pre-designed siRNA Set A
HY-RS09219
Epigenetics
LRFN2 Human Pre-designed siRNA Set A
LRFN2 Human Pre-designed siRNA Set A
HY-RS07782
Epigenetics
Luteolin 7-sulfate
Luteolin 7-sulfate
HY-N6901
Epigenetics
VRTN Human Pre-designed siRNA Set A
VRTN Human Pre-designed siRNA Set A
HY-RS15705
Epigenetics