GENERAL CATALOGUE
JAK3-IN-11
HY-146727 · 50 mg
MedChemExpress · Cat: HY-146727
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Manufacturer product page
medchemexpress.com/jak3-in-11.htmlCatalog No: HY-146727
CAS No: 2412734-00-8
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
JAK3-IN-11 Compound 12 , a potent, noncytotoxic, irreversible, orally active JAK3 inhibitor with IC50 value of 1.7 nM, has excellent selectivity 588-fold compared to other JAK isoforms, covalently bind to the ATP-binding pocket in JAK3. JAK3-IN-11 strongly inhibits JAK3-dependent signaling and T cell proliferation, is a promising tool for study autoimmune diseases.
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