JAK3 Mouse Monoclonal Antibody

Description

EnkiLife offers the JAK3 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ICC,ELISA,FC application. Alternative Names of Immunogen: JAKL; LJAK. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Research Area: PI3K-Akt signaling pathway,Jak-STAT signaling pathway