GENERAL CATALOGUE
JB300
HY-172144 · 1 mg
MedChemExpress · Cat: HY-172144
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Catalog No: HY-172144
CAS No: 3038446-90-8
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
JB300 is a highly selective Aurora A degrader based on PROTAC technology DC50=30 nM . JB300 can be used for tumor research. JB300 consists of PROTAC target protein ligand MK-5108 HY-13252 pink part , E3 ligase ligand Thalidomide-O-COOH HY-103597 blue part and PROTAC Linker Boc-NH-PEG2-C2-NH2 HY-W008474 black part , of which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc HY-172145 .
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