

HY-153450 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153450
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medchemexpress.com/jbi-589.htmlDescription
JBI-589 is a non-covalent PAD4 isoform-selective inhibitor with oral bioavailability. JBI-589 reduces CXCR2 expression and blocks neutrophil chemotaxis. JBI-589 reduces primary tumor and metastases, and enhances the anti-tumor effect of checkpoint inhibitors. JBI-589 can be used in cancer research.

