GENERAL CATALOGUE
JH-RE-06-d6
HY-126214S · 1 mg
MedChemExpress · Cat: HY-126214S
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medchemexpress.com/jh-re-06-d6.htmlCatalog No: HY-126214S
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
JH-RE-06-d6 is deuterium labele JH-RE-06. JH-RE-06, a potent REV1-REV7 interface inhibitor IC50=0.78 ?M; Ki=0.42 ?M , targets REV1 that interacts with the REV7 subunit of POL?. JH-RE-06 disrupts mutagenic translesion synthesis TLS by preventing recruitment of mutagenic POL?. JH-RE-06 improves chemotherapy.