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JHU37152
GENERAL CATALOGUE

JHU37152

HY-131891 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-131891

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Manufacturer product page

medchemexpress.com/jhu37152.html
Catalog No: HY-131891
CAS No: 2369979-67-7
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

JHU37152 is a potent and brain-penetrant DREADD agonist, with EC50s of 5?nM and 0.5?nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37152 exhibits selective 3H Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.

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