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JI6
GENERAL CATALOGUE

JI6

HY-18949 · 1 mg

MedChemExpress · Cat: HY-18949

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Manufacturer product page

medchemexpress.com/ji6.html
Catalog No: HY-18949
CAS No: 856436-16-3
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress

Description

JI6 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ?40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits JAK3 and c-Kit, with IC50s of ?250 and ?500 nM, respectively. JI6 can be used for the research of acute myeloid leukemia.

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