GENERAL CATALOGUE
JMV 3002
HY-129207 · 100 g
MedChemExpress · Cat: HY-129207
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medchemexpress.com/jmv-3002.htmlCatalog No: HY-129207
CAS No: 925239-03-8
Category: GPCR G Protein
Pack Size: 100 g
Brand: MedChemExpress
Description
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. 80 ?g/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98 % in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 ?g/kg.
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