GENERAL CATALOGUE
JMV6944
HY-162738 · 50 mg
MedChemExpress · Cat: HY-162738
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Catalog No: HY-162738
CAS No: 2871774-93-3
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
JMV6944 is a PXR agonist. JMV6944 competitively inhibits hPXR ligand-binding domain LBD binding to PXR with an IC50 of 680nM. JMV6944 induces CYP3A4 mRNA expression in freshly isolated human primary human hepatocyte cultures. JMV6944 can be used for the synthesis of PROTAC PXR degrader JMV7048 HY-162704 .
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