GENERAL CATALOGUE
JMX0293
HY-144638 · 50 mg
MedChemExpress · Cat: HY-144638
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medchemexpress.com/jmx0293.html
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Catalog No: HY-144638
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
JMX0293 is an O-alkylamino-tethered salicylamide derivative compound. JMX0293 maintains good potency against MDA-MB-231 cell line IC50 = 3.38 ?M while exhibiting very low toxicity against human non-tumorigenic breast epithelial cell line MCF-10A IC50 60 ?M. JMX0293 inhibits STAT3 phosphorylation and contribute to apoptosis in TNBC MDA-MB-231 cells. JMX0293 significantly suppresses MDA-MB-231 xenograft tumor growth in vivo without significant toxicity.
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