GENERAL CATALOGUE
JNJ-1250132
HY-123163 · 50 mg
MedChemExpress · Cat: HY-123163
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medchemexpress.com/jnj-1250132.htmlCatalog No: HY-123163
CAS No: 240805-96-3
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
JNJ-1250132 RWJ-66826 is an orally active and potent steroidal progesterone receptor PR antagonist, with an IC50 of 1.3 nM. JNJ-1250132 inhibits binding of the receptor to DNA in vitro. JNJ-1250132 is a potent competitive inhibitor of binding to the human glucocorticoid receptor GR IC50=0.50 nM and the rat androgen receptor AR IC50=5.6 nM , and was a weak inhibitor of binding to human Estrogen receptor ER IC50 3000 nM.
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