GENERAL CATALOGUE
JNJ-16241199
HY-10226 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10226
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medchemexpress.com/jnj-16241199.htmlCatalog No: HY-10226
CAS No: 604769-01-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
JNJ-16241199 R306465 is an orally active, selectivehydroxamate-based histone deacetylase HDAC inhibitor, with theIC50of 3.3 nM and 23 nM for HDAC1and HDAC8, respectively.JNJ-16241199induces histone 3 acetylation and strongly increases the expression of p21waf1, cip1 in A2780 ovarian carcinoma cells.JNJ-16241199 inducescell apoptosisand shows anticancer activityin a broad spectrum of human malignancies. JNJ-16241199 can be used for cancer study.
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