GENERAL CATALOGUE
JNJ-54717793
HY-134188 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-134188
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Manufacturer product page
medchemexpress.com/jnj-54717793.htmlCatalog No: HY-134188
CAS No: 1628843-99-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor OX1R antagonist plasma EC50=85 ng/mL . The Ki values of JNJ-54717793 for hOX1R human OX1R and hOX2R are 16 nM and 700 nM, respectively. JNJ-54717793 is a potent compound of anxiety disorders.
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