GENERAL CATALOGUE
JNJ-7777120
HY-13508 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-13508
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medchemexpress.com/JNJ-7777120.htmlCatalog No: HY-13508
CAS No: 459168-41-3
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
JNJ-7777120 is a potent and selective histamine H4 receptor antagonist Ki=4.5 nM . JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory.
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