GENERAL CATALOGUE
JNJ10191584
HY-123532 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-123532
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Manufacturer product page
medchemexpress.com/jnj10191584.htmlCatalog No: HY-123532
CAS No: 73903-17-0
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
JNJ10191584 VUF6002 is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 ?M. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively.
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