GENERAL CATALOGUE
JNJ10191584 maleate
HY-107558 · 50 mg
MedChemExpress · Cat: HY-107558
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medchemexpress.com/jnj10191584-maleate.htmlCatalog No: HY-107558
CAS No: 869497-75-6
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
JNJ10191584 VUF6002 maleate compound 40 is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H4 receptor over the H3 receptor with a Ki value of 14.1 ?M. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively.
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