GENERAL CATALOGUE
JNU-0921
HY-161982 · 5 mg
MedChemExpress · Cat: HY-161982
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Manufacturer product page
medchemexpress.com/jnu-0921.htmlCatalog No: HY-161982
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
JNU-0921 is a potent and orally active CD137 agonist. JNU-0921 increases the mRNA expression of IFN-? and GZMB. JNU-0921 induces luciferase activity with an EC50 value of 64.07 nM.JNU-0921 enhances effector and memory function of cytotoxic CD8+ T cells CTLs and alleviates their exhaustion. JNU-0921 also skews polarization of helper T cells toward T helper 1 type and enhances their activity to boost CTL function. JNU-0921 shows anticancer activity.
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