GENERAL CATALOGUE
JT002
HY-149478 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-149478
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medchemexpress.com/jt002.htmlCatalog No: HY-149478
CAS No: 2238820-43-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
JT002 is an orally active and selective NLRP3 inflammasome assembly inhibitor. JT002 reduces NLRP3-dependent proinflammatory cytokine such as IL-1?, IL-1?, IL-18 production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice. JT002 can be used for the study of a variety of inflammatory diseases, such as Muckle-Wells syndrome MWS .