GENERAL CATALOGUE
JTT-553
HY-123765 · 50 mg
MedChemExpress · Cat: HY-123765
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/jtt-553.html
Sponsored
Catalog No: HY-123765
CAS No: 701232-94-2
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
JTT-553 is a DGAT1 inhibitor IC50: 2.38 nM . JTT-553 reduces plasma concentrations of glucose, insulin, non-esterified fatty acids NEFA , total cholesterol TC , and hepatic triglycerides TG . JTT-553 improves insulin-dependent glucose uptake and glucose intolerance in adipose tissue of DIO mice. JTT-553 reduces TNF-? mRNA levels and increases GLUT4 mRNA levels in adipose tissue of KK-Ay mice. JTT-553 improves adipose tissue insulin resistance and systemic glucose metabolism by reducing body weight. JTT-553 can be used in the study of obesity and type 2 diabetes mellitus T2DM .
More from MedChemExpress
(R)-Trolox (Standard)
HY-101445AR
Metabolic Enzyme Protease
Propentofylline-d6
HY-107203S
Metabolic Enzyme Protease
PTP1B-IN-2
HY-100462
Metabolic Enzyme Protease
Stearic acid-PEG-Mal, MW 2000
HY-W440950
Metabolic Enzyme Protease
Enazadrem phosphate
HY-U00024A
Metabolic Enzyme Protease
1,2-Dihexanoyl-sn-glycero-3-phosphocholine
HY-W127457
Metabolic Enzyme Protease
(R)-KT109
HY-126031
Metabolic Enzyme Protease
?-Glucosidase-IN-31
HY-149409
Metabolic Enzyme Protease