GENERAL CATALOGUE
JWJ-01-378
HY-175271 · 50 mg
MedChemExpress · Cat: HY-175271
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/jwj-01-378.htmlCatalog No: HY-175271
Category: MAPK ERK Pathway
Pack Size: 50 mg
Brand: MedChemExpress
Description
JWJ-01-378 is a selective TRK PROTAC degrader. JWJ-01-378 efficiently degrades WT TRK and TPM3-TRKA fusion proteins and inhibits downstream pERK signaling, while showing limited efficacy against TRK inhibitor resistant mutants and ALK fusions. JWJ-01-378 potently suppresses cancer cell proliferation.Pink: TRK ligand HY-160520 ; Blue: CRBN ligase ligand HY-103596 ; Black: linker
More from MedChemExpress
?-Glycerophosphate disodium salt pentahydrate
HY-D0886
MAPK ERK Pathway
WZH-17-002
HY-174315
MAPK ERK Pathway
D-87503
HY-108959
MAPK ERK Pathway
LC-SF-14
HY-172916
MAPK ERK Pathway
MCB-22-174
HY-165607S
MAPK ERK Pathway
MAP855
HY-145702
MAPK ERK Pathway
SHR2415
HY-151367
MAPK ERK Pathway
Cuspin-1
HY-119460
MAPK ERK Pathway