GENERAL CATALOGUE
K145 hydrochloride
HY-15779A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15779A
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Catalog No: HY-15779A
CAS No: 1449240-68-9
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 ?M and a Ki of 6.4 ?M. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.
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